Immunological Studies on Human Placental Lactogen (HPL)
نویسندگان
چکیده
منابع مشابه
Human placental lactogen (hPL) deficiency in a normal pregnancy.
A case of human placental lactogen (hPL) deficiency together with normal oestriol levels associated with a normal pregnancy in a woman in her second pregnancy is reported. The woman gave birth to a healthy male infant. The placenta was normal. Extremely low hPL levels may be compatible with the delivery of a healthy infant.
متن کاملSerum human placental lactogen (HPL) levels in normal pregnancy.
It is now well established that human placenta secretes a protein hormone Human Placental Lactogen (HPL), also referred to as placental Somatomarnmotropin. It shows immunological crossreactivity with pituitary growth hormone and possesses both mammotropi.c and somatotropic effects (Jasiomovich and Maclaren, 1962, Kaplan and Grumbach 1968). This hormone is produced by syncytiotrophoblast layer o...
متن کاملIn vitro biosynthesis of human placental lactogen (HPL) by chorionic tissue and the diagnostic value of HPL in trophoblastic disease.
With an aim to elucidate the significance of Human Placental Lactogen (HPL) during gestation, I assayed the HPL and HCG concentration in the chorionic tissue and the blood. The results as follows: 1) There was a definite correlation between the HPL concentration in the maternal serum at term and the weight of the neonates, which might lead to an idea that HPL took part in the growth of fetuses ...
متن کاملHuman placental lactogen (hPL-A) activates signaling pathways linked to cell survival and improves insulin secretion in human pancreatic islets.
The search for factors either promoting islets proliferation or survival during adult life is a major issue for both type 1 and 2 diabetes mellitus. Among factors with mitogenic activity on pancreatic β-cells, human placental lactogen (hPL) showed stronger activity when compared to the other lactogen hormones: growth hormone (GH) and prolactin (PRL). The aim of the present work is to elucidate ...
متن کاملEctopic production of human placental lactogen by human breast tumors.
Serum samples from 72 patients with established carcinoma of the breast were investigated for ectopic presence of hPL. Further, the relationship of ectopically-secreted hPL and hCG-beta in breast cancer was investigated. Ten of 72 patients examined had detectable hPL and 12 had detectable hCG-beta, at 1-2 ng/ml serum sensitivity of the assay. The presence of hPL in serum of breast cancer patien...
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ژورنال
عنوان ژورنال: Folia Endocrinologica Japonica
سال: 1970
ISSN: 0029-0661
DOI: 10.1507/endocrine1927.46.7_814